ABSTRACT
Objective To analyze the clinical efficacy of using virtual reality ( VR) to improve the upper limb function of hemiplegic persons. Methods A search was conducted in the PubMed, Cochrane Library, EM-BASE, CNKI and Wanfang Data as well as VIP for reports of randomized and controlled studies of using VR in train-ing upper limb function after stroke. A meta-analysis was then performed using version 5. 3 of the Review Manager software. Results Ninety studies involving 879 patients were found and analyzed. The data showed that VR was sig-nificantly more effective than conventional training in improving Fugl-Meyer assessment scores. It was not superior, however, in improving average Functional Independence Measure scores or performance in the box and blocks test. Conclusion VR is superior to conventional training in promoting the recovery of upper limb function after a stroke.
ABSTRACT
Objective To investigate the effects of atorvastatin combined with aspirin on carotid atherosclerotic plaque and blood biochemical parameters in patients with minor stroke.Methods 120 patients with acute minor stroke were randomly divided into A group,B group and C group,40 cases in each group in 40 cases.On the basis of conventional treatment,A B,C groups,were given 10,20,40mg atorvastatin + 100mg aspirin,continuous medication for 6 months.Before and after treatment,the lipid metabolism and oxidation indexesindices,blood rheological parameters,carotid IMT and plaque area were compared among the three groups.Results After treatment,TC,TG,LDL,HOMA-IR,IMT and plaque area were significantly decreased in all groups (t =12.687,3.653,10.590,3.675,all P ＜0.05),and TC,TG,LDL,HOMA-IR,IMT and plaque area of C group were significantly lower than those of A group and B group,the differences were statistically significant(F =63.315,5.987,4.876,4.354,3.657,3.887,all P ＜0.05).After treatment,fibrinogen,plasma viscosity,erythrocyte rigidity index and hs-CRP were significantly decreased(t =3.437,4.325,3.876,3.487,all P ＜ 0.05).And the hs-CRP of C group were was significantly lower than those that of A group and B group,the difference was statisticallysignificant(F =4.532,P ＜ 0.05).Conclusion Atorvastatin combined with aspirin can significantly improve the carotid atherosclerotic plaque and blood biochemical parametersindexes in patients with minor stroke,and high dose atorvastatin has better effect in on patients with'carotid plaque,lipid metabolism and inflammatory reaction better effect.